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Mayo Clinic Proceedings: Innovations, Quality & Outcomes
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      • Case report
        Open Access

        Esophageal Stricture Following Radiation, Concurrent Immunochemotherapy, Treated With Hyperbaric Oxygen and Dilation

        Mayo Clinic Proceedings: Innovations, Quality & Outcomes
        Vol. 3Issue 2p241–245Published in issue: June, 2019
        • Olayinka D. Ajayi
        • Cadman L. Leggett
        • Sarel J. Myburgh
        • Stephen M. Hendriksen
        • Christopher J. Logue
        • Joseph W. Walter
        • and others
        Cited in Scopus: 0
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          Low-dose palliative radiation may offer symptomatic relief in patients with spinal metastases from primary renal cell cancer and is unlikely to result in radiation injury. Patients with advanced malignancy requiring palliative radiation are often also receiving chemotherapy. Synergistic adverse effects resulting from combined palliative radiation and novel antiprogrammed cell death-1 (anti-PD 1) and/or multityrosine kinase inhibitors are rare. We report about a 60-year-old woman with metastatic clear-cell renal cancer, status post-left nephrectomy, with debilitating mid-back pain from metastatic tumor burden and foraminal nerve compression.
          Esophageal Stricture Following Radiation, Concurrent Immunochemotherapy, Treated With Hyperbaric Oxygen and Dilation
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