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Mayo Clinic Proceedings: Innovations, Quality & Outcomes
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      Open Access

      Brachial Plexus Neuritis Associated With Anti–Programmed Cell Death-1 Antibodies: Report of 2 Cases

      Mayo Clinic Proceedings: Innovations, Quality & Outcomes
      Vol. 1Issue 2p192–197Published in issue: September, 2017
      • Reem M. Alhammad
      • Roxanna S. Dronca
      • Lisa A. Kottschade
      • Heidi J. Turner
      • Nathan P. Staff
      • Michelle L. Mauermann
      • and others
      Cited in Scopus: 0
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        Recently, guidelines have been outlined for management of immune-related adverse events occurring with immune checkpoint inhibitors in cancer, irrespective of affected organ systems. Increasingly, these complications have been recognized as including diverse neuromuscular presentations, such as demyelinating and axonal length–dependent peripheral neuropathies, vasculitic neuropathy, myasthenia gravis, and myopathy. We present 2 cases of brachial plexopathy developing on anti–programmed cell death-1 checkpoint inhibitor therapies (pembrolizumab, nivolumab).
        Brachial Plexus Neuritis Associated With Anti–Programmed Cell Death-1 Antibodies: Report of 2 Cases
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