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    Open Access

    Prosthetic Joint Infections Due to Histoplasma capsulatum: A Report of 3 Cases

    Mayo Clinic Proceedings: Innovations, Quality & Outcomes
    Vol. 5Issue 1p225–229Published online: January 20, 2021
    • Hadi E. Berbari
    • Pooja Gurram
    • Maryam Mahmood
    • Paul J. Deziel
    • Randall C. Walker
    • Raymund R. Razonable
    Cited in Scopus: 0
      Histoplasma capsulatum causes pneumonia and multisystemic disease in humans. Musculoskeletal involvement in histoplasmosis is most often tenosynovitis and rarely septic arthritis. Even more uncommon is the involvement of prosthetic joints. Here, we report a series of 3 cases of prosthetic joint failures caused by infection due to H capsulatum. Together with a review of 4 previously reported cases, we summarize host characteristics, clinical presentation, surgical approaches, antifungal management, and outcomes of this rare orthopedic joint infection.

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