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    Successful Renal Outcome in Membranoproliferative Glomerulonephritis Following Treatment of the Underlying Subtle Clone: A Case Report

    Mayo Clinic Proceedings: Innovations, Quality & Outcomes
    Vol. 2Issue 3p297–302Published online: June 5, 2018
    • Ritika Rana
    • Paul Cockwell
    • Bindu Vydianath
    • Mark Cook
    • Guy Pratt
    • Mark Trehane Drayson
    • and others
    Cited in Scopus: 0
      Membranoproliferative glomerulonephritis (MPGN) secondary to a monoclonal gammopathy is a rare glomerular disease and is defined as a monoclonal gammopathy of renal significance. The disease is characterized by glomerular monotypic immunoglobulin deposits and specific changes on light microscopy and electron microscopy. Immunochemistry is required to establish monoclonality, and electron microscopy helps to characterize the deposits ultrastructurally. Investigation for the underlying monoclonal protein should be done.
      Successful Renal Outcome in Membranoproliferative Glomerulonephritis Following Treatment of the Underlying Subtle Clone: A Case Report

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