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Mayo Clinic Proceedings: Innovations, Quality & Outcomes
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    • Editorial1

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    • Commentary
      Open Access

      Never Waste a Pandemic: Strategies to Increase Advance Care Planning Now

      Mayo Clinic Proceedings: Innovations, Quality & Outcomes
      Vol. 5Issue 5p946–950Published online: September 18, 2021
      • Adebisi Alli
      • Bjorg Thorsteinsdottir
      • Elise C. Carey
      • Rachel D. Havyer
      Cited in Scopus: 0
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        Coronavirus disease 2019 (COVID-19)–related deaths and hospitalizations have created a global health crisis with unprecedented scarcity of health care resources and staffing in parts of the United States and around the world. The pandemic has led to important discussions about just allocation of health care resources. News headlines about COVID-19 feature family members who announce hospitalized loved ones died after treatment options were denied. Other articles demonstrate that patients may not fully understand the ramifications of elected care in an intensive care setting, unpredictability of outcomes, and how this may impact future abilities.
      • Commentary
        Open Access

        Harry Lee Parker: Games Lost and Won on the Playing Fields of Neurology

        Mayo Clinic Proceedings: Innovations, Quality & Outcomes
        Vol. 5Issue 4p701–719Published online: July 15, 2021
        • Christopher J. Boes
        • James P. Klaas
        • W. Oliver Tobin
        • Eoin P. Flanagan
        • Andrew McKeon
        • Sherri A. Braksick
        • and others
        Cited in Scopus: 0
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          Harry Lee Parker (1894–1959) was an American and Irish neurologist who reported unique paroxysmal symptoms in patients with multiple sclerosis,1 and wrote a book on clinical neurology popular enough to be reprinted 13 years after initial publication.2 Parker penned profiles of other physicians,3-5 but his biography has only been touched on briefly in obituaries,6,7 articles,1,8,9 and books.10-13 Following his advice that “a honeyed obituary is an insult to the dead (p. 596),”5 we will describe in detail the life of Dr.
          Harry Lee Parker
        • Commentary
          Open Access

          The Team Approach to Spinal Cord and Dorsal Root Ganglion Stimulation: A Guide for the Advanced Practice Provider

          Mayo Clinic Proceedings: Innovations, Quality & Outcomes
          Vol. 5Issue 3p663–669Published online: May 22, 2021
          • Jonathan M. Hagedorn
          • Brittney Misercola
          • Ashley Comer
          • Jeanmarie Tari-Blake
          • Chelsey M. Hoffmann
          • Pankaj Mehta
          • and others
          Cited in Scopus: 0
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            Because of shortages in the US primary care workforce in the 1960s, the role of the nurse practitioner and physician assistant emerged.1 The tasks of these individuals are often considered similar, and together they are known as advanced practice providers (APPs). The nurse practitioner is an advanced practice registered nurse who has completed additional training and education, earning a master’s or doctoral degree. Physician assistants train for an additional 2 years beyond a Bachelor of Arts or Science degree to earn a physician assistant degree.
          • Commentary
            Open Access

            2020—The Year the World Was Awakened to the Importance of Supply Chain Management

            Mayo Clinic Proceedings: Innovations, Quality & Outcomes
            Vol. 5Issue 1p187–192Published online: January 16, 2021
            • James R. Francis
            • Bruce M. Mairose
            • Eric M. Tichy
            Cited in Scopus: 0
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              Some consumers have an understanding of and appreciation for the importance of supply chains. However, most also take for granted that a supply chain performs flawlessly. Over many years, we have been lulled into a false sense of supply chain stability and security. From the consumer perspective, this belief is primarily the result of a product being immediately available when we shop or having it delivered the next day to our doorstep from a fulfillment center. When this happens, the obvious conclusion is, “it must be working.” The coronavirus disease 2019 (COVID-19) pandemic challenges conventional wisdom related to the resiliency and agility of the supply chains in health care and many other industries.
              2020—The Year the World Was Awakened to the Importance of Supply Chain Management
            • Commentary
              Open Access

              Learning Health System in Crisis: Lessons From the COVID-19 Pandemic

              Mayo Clinic Proceedings: Innovations, Quality & Outcomes
              Vol. 5Issue 1p171–176Published online: October 29, 2020
              • Robert J. Romanelli
              • Kristen M.J. Azar
              • Sylvia Sudat
              • Dorothy Hung
              • Dominick L. Frosch
              • Alice R. Pressman
              Cited in Scopus: 0
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                The coronavirus disease 2019 (COVID-19) pandemic is the gravest public health crisis that the United States has seen in more than a century. Health care delivery systems are the focal point for interfacing with COVID-19; however, many were and remain unprepared for this or similar outbreaks. In this article, we describe the learning health system (LHS) as an ideal organizing principle to inform an evidence-based response to public health emergencies like COVID-19. We further describe barriers and challenges to the realization of the LHS and propose a call to action for a substantial investment in the LHS, with a focus on public health.
              • Commentary
                Open Access

                Reciprocal Development and Progressive Responsibility: The History of the Mayo Clinic Neurology Residency

                Mayo Clinic Proceedings: Innovations, Quality & Outcomes
                Vol. 4Issue 5p478–498Published in issue: October, 2020
                • Christopher J. Boes
                • David B. Burkholder
                • Elizabeth A. Coon
                • Jeremy K. Cutsforth-Gregory
                • James P. Klaas
                • Lyell K. Jones Jr.
                Cited in Scopus: 0
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                  The first Mayo Clinic neurology resident began training approximately 1 century ago. Over the subsequent 100 years, 639 budding specialists in diseases of the nervous system graduated from the Mayo Clinic Neurology Residency in Rochester, Minnesota. The history of the American residency has been thoroughly covered by Ludmerer in his 2014 book Let Me Heal,1 and a history of the Mayo Clinic Otolaryngology Residency Program was published in 2020.2 Mulder discussed education in the Mayo Clinic Department of Neurology as part of an overview of the history of the department in 1971.
                  Reciprocal Development and Progressive Responsibility: The History of the Mayo Clinic Neurology Residency
                • Commentary
                  Open Access

                  Balancing Unbalanced Lives: A Practical Framework for Personal and Organizational Change

                  Mayo Clinic Proceedings: Innovations, Quality & Outcomes
                  Vol. 3Issue 1p97–100Published in issue: March, 2019
                  • Carole M. Warde
                  • Mark Linzer
                  • John B. Schorling
                  • Elizabeth M. Moore
                  • Sara Poplau
                  Cited in Scopus: 0
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                    Rising rates of physician burnout have led to efforts to decrease stress in clinical environments. Although mild to moderate stress can improve productivity, prolonged or sustained stress becomes “distress,” as revealed by national statistics on physician burnout.1 Burnout can affect personal relationships and disrupt family life. Professionally, burnout can harm patient care, relationships with patients and colleagues, a person's integrity, and, eventually, the viability of our health care system, as providers exit prematurely and patients lose confidence in their care.
                    Balancing Unbalanced Lives
                  • Commentary
                    Open Access

                    Survival With Auricular Fibrillation: The View From a Century Ago at the Mayo Clinic

                    Mayo Clinic Proceedings: Innovations, Quality & Outcomes
                    Vol. 3Issue 1p101–102Published in issue: March, 2019
                    • Jamie Newman
                    • Renee E. Ziemer
                    Cited in Scopus: 0
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                      Atrial fibrillation is a common disease affecting millions of Americans. A century ago, it was a less regularly recognized phenomenon. With the advent of the electrocardiogram (ECG), this arrhythmia could be more readily identified. Frederick Willius, the first specialist in cardiology at the Mayo Clinic Rochester, became interested in the survival of patients with this condition. Using the tools at hand, he studied the outcome of 500 patients found to have ECG changes consistent with auricular fibrillation, as the condition was known at that time.
                      Survival With Auricular Fibrillation: The View From a Century Ago at the Mayo Clinic
                    • Commentary
                      Open Access

                      Offshore Pharmaceutical Trials: Evidence, Economics, and Ethics

                      Mayo Clinic Proceedings: Innovations, Quality & Outcomes
                      Vol. 2Issue 3p226–228Published online: June 5, 2018
                      • Y. Tony Yang
                      • Brian Chen
                      • Charles L. Bennett
                      Cited in Scopus: 0
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                        Backed by a group of wealthy investors and an American university, a US pharmaceutical company recently flouted United States Food and Drug Administration (FDA) safety protections by testing an experimental herpes vaccine offshore.1 More than 20 American patients with herpes were flown to St Kitts several times to be vaccinated.1 By participating in a study that was not monitored by the FDA or a safety panel, patients forewent mandated layers of protection against dangerous adverse effects or even death.
                      • Commentary
                        Open Access

                        Integrated Care: A Disruptive Innovation for Extending Psychiatric Expertise to Primary Care Practices

                        Mayo Clinic Proceedings: Innovations, Quality & Outcomes
                        Vol. 2Issue 2p99–102Published online: May 2, 2018
                        • Akuh Adaji
                        Cited in Scopus: 0
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                          Behavioral health disorders (mental health problems and substance use disorders) are highly prevalent, negatively impact chronic medical illness, and raise the overall cost of health care from increased emergency department utilization, hospital readmission rates, and occupational disability.1-3 Psychiatrists make up a scarce and expensive resource needed to address the demand for treatment of patients with behavioral health disorders. Patients in rural areas are even more in need as problems with access and capacity persist, particularly as psychiatrists are located primarily in major cities and urban areas.
                        • Editorial
                          Open Access

                          The Challenging Conundrum of Diagnosing and Managing Clostridium difficile Infection

                          Mayo Clinic Proceedings: Innovations, Quality & Outcomes
                          Vol. 1Issue 1p5–7Published online: June 13, 2017
                          • Dale N. Gerding
                          • Stuart Johnson
                          Cited in Scopus: 0
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                            Management of patients with Clostridium difficile infection (CDI) can be very difficult, especially for the approximately 25% of patients who have had recurrences, and particularly for those who have had multiple recurrences. Following recurrence, patients typically respond to a new course of antimicrobial treatment, usually with vancomycin or fidaxomicin, but often have another recurrence within a few days to months after stopping treatment. Although treatment failure to resolve symptoms is not uncommon when metronidazole is used,1 failure to resolve symptoms when treated with a new course of antimicrobial treatment with either vancomycin or fidaxomicin is an indication that a condition other than CDI may be the cause of the patient's symptoms.
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