The first Mayo Clinic neurology resident began training approximately 1 century ago. Over the subsequent 100 years, 639 budding specialists in diseases of the nervous system graduated from the Mayo Clinic Neurology Residency in Rochester, Minnesota. The history of the American residency has been thoroughly covered by Ludmerer in his 2014 book Let Me Heal,1 and a history of the Mayo Clinic Otolaryngology Residency Program was published in 2020.2 Mulder discussed education in the Mayo Clinic Department of Neurology as part of an overview of the history of the department in 1971.